Patent · US Active

Nanoparticle and magnetic resonance imaging contrast agent

US8344102B2 · kind B2 · utility

1Cited by
0References
8Claims
0Family size

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Key dates

Filing dateApr 14, 2010
Grant dateJan 1, 2013
Priority date—
Expiry dateJan 22, 2031

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2446/90
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A nanoparticle contains a core including superparamagnetic nanoparticles and having an outer surface, and siloxanyl moieties covalently coupled to the outer surface of the core and having Formula (I):In formula (I): X1 and X2 independently represent methylene, ethylene or propylene; R represents an optionally substituted pyridyl group, or —S—R is a group derived from a targeting ligand containing —SH group and effective to bind specifically with a predetermined targeted cell in an object; n and m independently represent an integer ranging from 1 to 3; and p represents an integer ranging from 9 to 45. The nanoparticles are suitable for use as a magnetic resonance imaging contrast agent.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.