System and method for surface plasmon resonance based detection of molecules
US8345253B2 · kind B2 · utility
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21Claims
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Key dates
| Filing date | Feb 21, 2008 |
| Grant date | Jan 1, 2013 |
| Priority date | — |
| Expiry date | Feb 21, 2028 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/2575
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A system and method for molecule detection uses a surface plasmon resonance (SPR) system with detection spots having fixed nanostructures. An SPR assembly may be combined with a digital microfluidic control system such as an electrowetting-on-dielectric (EWOD) chip. The microfluidic system individually directs sample droplets to different detection spots of the SPR assembly, thus allowing the SPR examination of different samples or sample reactions on the same surface. The nanostructures at the detection spots enhance the sensitivity of the SPR signals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.