Immunoglobulin formulation and method of preparation thereof
US8349321B2 · kind B2 · utility
54Cited by
8References
4Claims
0Family size
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Key dates
| Filing date | Oct 2, 2009 |
| Grant date | Jan 8, 2013 |
| Priority date | — |
| Expiry date | Oct 2, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.