Controlled release cytotoxic agent compositions and methods for the treatment of otic disorders

US8349353B2 · kind B2 · utility

Assignees

• OTONOMY, INC. · US
• The Regents of the University of California · US

Inventors

• Jay Lichter · Rancho Santa Fe, US
• Andrew M. Trammel · Olathe, US
• Jeffrey P. Harris · Village of La Jolla, US
• Carl Lebel · Malibu, US
• Fabrice Piu · San Diego, US
• Qiang Ye · San Diego, US
• Luis A. Dellamary · San Marcos, US

Key dates

• Filing date: Jun 29, 2009
• Grant date: Jan 8, 2013
• Expiry date: Feb 16, 2031

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/0046
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with cytotoxic agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).