Nucleic acid coated particles suitable for temporary storage
US8349364B2 · kind B2 · utility
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14References
47Claims
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Key dates
| Filing date | Sep 29, 2003 |
| Grant date | Jan 8, 2013 |
| Priority date | — |
| Expiry date | Oct 4, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2730/10122
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Particles are provided which are suitable for delivery from a particle-mediated delivery device. The particles are obtained by precipitating a nucleic acid on inert metal carrier particles in the presence of a nucleic acid condensing agent and a metal ion chelating agent. Also described are processes for preparing the particles, and therapeutic methods using the particles including methods of nucleic acid immunization and gene therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.