Patent · US Active

Galectin-3 cleavage as a marker for matrix metalloproteinase activity in cancer

US8349579B2 · kind B2 · utility

3Cited by

0References

6Claims

0Family size

Assignee

Wayne State University · US

Inventors

Avraham Raz · Beverly Hills, US
Pratima Nangia-Makker · Troy, US
Rafael Fridman · Beverly Hills, US

Key dates

Filing date	Dec 11, 2008
Grant date	Jan 8, 2013
Priority date	—
Expiry date	Feb 6, 2030

Classification

Technology area (CPC G)Physics
CPC primaryG01N2333/96486
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Provided are differential antibodies recognizing the cleaved and non-cleaved forms of matrix metalloproteinases (MMPs), and methods of using the antibodies as surrogate diagnostic markers for the presence of active MMPs in cancer, such as growing breast cancers.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.