Process for the preparation of ring compounds

US8350100B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Detlef Pauluth · Ober-Ramstadt, DE
• Peer Kirsch · Darmstadt, DE
• Peter Baeuerle · Ludwigsburg, DE
• Oliver Deeg · Monsheim, DE

Key dates

• Filing date: Feb 16, 2012
• Grant date: Jan 8, 2013
• Expiry date: Feb 16, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C09K2019/124
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

In a process for the preparation of ring compounds via a combinatorial synthesis, the reaction procedure is based on a Suzuki coupling; subsequent halo-demetallation and finally a further Suzuki coupling. The Suzuki couplings are each carried out with a boronic acid or a boronic acid ester. The reaction procedure uses provides novel ring compounds and uses novel synthesis units used for this purpose. The novel ring compounds are suitable for use as constituents in liquid-crystalline mixtures.