Compositions and methods for the prevention and treatment of autoimmune conditions
US8354110B2 · kind B2 · utility
29Cited by
22References
21Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Mar 7, 2008 |
| Grant date | Jan 15, 2013 |
| Priority date | — |
| Expiry date | May 15, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/042
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The methods include selectively reducing or expanding T cells according to the antigenic specificity of the T cells. Therefore, the present invention can be used to reduce or eliminate pathogenic T cells that recognize autoantigens, such as beta cell specific T cells. As such, the present invention can be used to prevent, treat or ameliorate autoimmune diseases such as IDDM. Furthermore, the present invention can be used to expand desirable T cells, such as anti-pathogenic T cells to prevent, treat and/or ameliorate autoimmune diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.