Multi plasmid system for the production of influenza virus
US8354114B2 · kind B2 · utility
30Cited by
6References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 17, 2006 |
| Grant date | Jan 15, 2013 |
| Priority date | — |
| Expiry date | Feb 25, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/16251
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Vectors and methods for the production of influenza viruses suitable as recombinant influenza vaccines in cell culture are provided. Bi-directional expression vectors for use in a multi-plasmid influenza virus expression system are provided. Additionally, the invention provides methods of producing influenza viruses with enhanced ability to replicate in embryonated chicken eggs and/or cells (e.g., Vero and/or MDCK) and further provides influenza viruses with enhanced replication characteristics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.