Transactivation system for mammalian cells
US8354251B2 · kind B2 · utility
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2Claims
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Key dates
| Filing date | Dec 30, 2004 |
| Grant date | Jan 15, 2013 |
| Priority date | — |
| Expiry date | Sep 6, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/63
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is directed generally to compositions and methods for expressing recombinant proteins in a mammalian host cell using a co-expressed transcriptional activator. In particular, the invention provides vectors, host cells, and methods of expressing at least one desired polypeptide by transfecting a mammalian host cell with cistrons encoding a transactivator, a desired polypeptide, and an apoptosis-protective protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.