Patent · US Active

Oxazolidinone amide aromatic compounds for supressing MMP-9 production

US8354401B2 · kind B2 · utility

8Cited by
0References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 27, 2009
Grant dateJan 15, 2013
Priority date
Expiry dateOct 27, 2029

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D413/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided are a novel low-molecular-weight compound that suppresses production of induction type MMPs, particularly MMP-9, rather than production of hemostatic type MMP-2, as well as a prophylactic/therapeutic drug for autoimmune diseases or osteoarthritis. An amide derivative represented by the following formula (I)wherein each symbol is as defined in the specification, a pharmacologically acceptable salt thereof, or a hydrate or solvate thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.