Patent · US Active

Skin treatments containing carboxylic acid-substituted idebenone derivatives and methods of preparation and use thereof

US8354550B2 · kind B2 · utility

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1References
4Claims
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Key dates

Filing dateJan 13, 2012
Grant dateJan 15, 2013
Priority date
Expiry dateJan 13, 2032

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2601/16
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to novel carboxylic acid-substituted idebenone derivatives, skin treatment compositions containing these carboxylic acid-substituted idebenone derivatives, methods of treating skin changes by topical application of these carboxylic acid-substituted idebenone derivatives, and their methods of synthesis. The carboxylic acid-substituted idebenone derivatives of the present invention are unexpectedly effective in treating skin, particularly with respect to skin tolerance. When included in a topical composition, the carboxylic acid-substituted idebenone derivatives of the present invention have an antioxidant effect that is useful in treating a skin change.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.