Plant acyltransferases specific for long-chained, multiply unsaturated fatty acids

US8354569B2 · kind B2 · utility

Assignee

• The University of Bristol · GB

Inventors

• Andreas Renz · Schifferstadt, DE
• Jörg Bauer · Weingarten, DE
• Margit Frentzen · Aachen, DE
• Nursen Sözer · Übach-Palenberg, DE
• Stobart Keith · Bristol, GB
• Thomas Fraser · Newton, US
• Colin M. Lazarus · Bristol, GB
• Baoxiu Qi · Bath, GB
• Amine Abbadi · Plettenberg, DE
• Ernst Heinz · Hamburg, DE

Key dates

• Filing date: Jul 28, 2010
• Grant date: Jan 15, 2013
• Expiry date: May 28, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P7/6472
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention relates to a process for the production of long-chain polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids coding for polypeptides with acyltransferase activity. These nucleic acid sequences, if appropriate together with further nucleic acid sequences coding for polypeptides of the fatty acid or lipid metabolism biosynthesis, can advantageously be expressed in the organism. Furthermore, the invention relates to a method for the production of oils and/or triacylglycerides with an elevated content of long-chain polyunsaturated fatty acids. The invention furthermore relates to the nucleic acid sequences, and constructs, vectors and organisms comprising the nucleic acid sequences. A further part of the invention relates to oils, lipids and/or fatty acids produced by the process according to the invention and to their use.