Method for identifying predictive biomarkers from patient data
US8355874B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 11, 2006 |
| Grant date | Jan 15, 2013 |
| Priority date | — |
| Expiry date | Nov 15, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16H50/20
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
The invention relates to a method for developing a biomarker for the prognosis of the result of a therapeutical treatment based on data obtained in clinical studies, data remaining unchanged by therapy being subdivided into diagnostic and genomic parameters and the marker being defined by a combination of parameters. The method according to the invention is characterized by specifying the maximum number of parameters for defining the marker and thus the maximum complexity of the system from the beginning and by carrying out the search for defining parameters by sequential combination of clinical parameters (=z parameters) and/or genomic parameters (=x parameters).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.