Patent · US Active

Method for identifying predictive biomarkers from patient data

US8355874B2 · kind B2 · utility

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7Claims
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Assignee

Inventors

Key dates

Filing dateDec 11, 2006
Grant dateJan 15, 2013
Priority date
Expiry dateNov 15, 2029

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG16H50/20
  • WIPO fieldComputer technology
  • WIPO sectorElectrical engineering

Abstract

The invention relates to a method for developing a biomarker for the prognosis of the result of a therapeutical treatment based on data obtained in clinical studies, data remaining unchanged by therapy being subdivided into diagnostic and genomic parameters and the marker being defined by a combination of parameters. The method according to the invention is characterized by specifying the maximum number of parameters for defining the marker and thus the maximum complexity of the system from the beginning and by carrying out the search for defining parameters by sequential combination of clinical parameters (=z parameters) and/or genomic parameters (=x parameters).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.