Annulus fibrosus detection in intervertebral discs using molecular imaging agents
US8357350B2 · kind B2 · utility
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Key dates
| Filing date | Feb 12, 2009 |
| Grant date | Jan 22, 2013 |
| Priority date | — |
| Expiry date | May 17, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to methods for imaging annulus fibrosus tissue and a quantitative measurement of its local concentration in a sample using an agent comprising the compound of Formula I, a 13C or 2H enriched compound of Formula I, an 19F-labeled derivative of Formula I, a metal-DOTA (1,4,7,10-tetra-azacyclododecane-N,N′,N″,N′″-tetraacetic acid) complex of Formula I, or a radioisotope derivative of Formula I.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.