Method of purifying influenza virus and removing MDCK cell DNA contaminants
US8357376B2 · kind B2 · utility
32Cited by
10References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 5, 2010 |
| Grant date | Jan 22, 2013 |
| Priority date | — |
| Expiry date | Jan 5, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/16252
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to novel MDCK cells which can be to grow viruses, e.g., influenza viruses, in cell culture to higher titer than previously possible. The MDCK cells can be adapted to serum-free culture medium. The present invention further relates to cell culture compositions comprising the MDCK cells and cultivation methods for growing the MDCK cells. The present invention further relates to methods for producing influenza viruses in cell culture using the MDCK cells of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.