Patent · US Active

Ansamycin formulations and methods of use thereof

US8357676B2 · kind B2 · utility

0Cited by

13References

22Claims

0Family size

Assignee

Infinity Discovery, Inc. · US

Inventors

Brian C. Austad · Tewksbury, US
Louis Grenier · Medford, US
Edward Holson · Newton, US
John J. Lee · Somerville, US
Roger H. Pak · Boxborough, US
James R. Porter · Rowley, US
James L. Wright · Springfield, US

Key dates

Filing date	Aug 20, 2008
Grant date	Jan 22, 2013
Priority date	—
Expiry date	Feb 9, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D225/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided herein, inter alia, are solid forms of geldanamycin analogs, pharmaceutical compositions comprising a geldanamycin analog and a crystallization inhibitor, methods of making and using such compositions. Additionally, provided are methods for the treatment of cancer, a neoplastic disease state and/or a hyperproliferative disorder, and methods of inhibiting Heat Shock Protein 90 (“Hsp90”).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.