Patent · US Active

Bicyclic angiotensin II agonists

US8357710B2 · kind B2 · utility

0Cited by

5References

19Claims

0Family size

Assignee

VICORE PHARMA AB · SE

Inventors

Mathias Alterman · Stockholm, SE
Anders Hallberg · Stockholm, SE
Murugaiah Andappan Murugaiah Subbaiah · Viralimalai, IN

Key dates

Filing date	Apr 12, 2006
Grant date	Jan 22, 2013
Priority date	—
Expiry date	May 15, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D333/40
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

There is provided a compound of formula I,wherein R1a, R1b, X, Y1, Y2, Y3, Y4, Z1, Z2, R2 and R3 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful as selective agonists of the AT2 receptor, and thus, in particular, in the treatment of inter alia gastrointestinal conditions, such as dyspepsia, IBS and MOF, and cardiovascular disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.