Methods of forming microparticle coated medical device
US8361539B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 15, 2003 |
| Grant date | Jan 29, 2013 |
| Priority date | — |
| Expiry date | Jan 24, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2300/622
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A drug-loaded microparticle is applied to a medical device for subsequent application to biological tissues. A method of formulating a drug-loaded microparticle and applying it to the surface of a medical device, such as a stent, is disclosed. The drug-loaded microparticle is formulated by combining a drug with various chemical solutions. Specified sizes of the microparticles and amounts of drug(s) contained within the microparticles may be varied by altering the proportions of the chemicals/solutions. In addition to various drugs, therapeutic substances and radioactive isotopes may also be loaded into the microparticles. The drug-loaded microparticle are suspended in a polymer solution forming a polymer matrix. The polymer matrix may be applied to the entire surface or only selected portions of the medical device via dipping, spraying or combinations thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.