Method for producing α-L-aspartyl-L-phenylalanine-β-ester and method for producing α-L-aspartyl-L-phenylalanine-α-methyl ester

US8361748B2 · kind B2 · utility

Assignee

• Ajinomoto Co., Inc.

Inventors

• Kenzo Yokozeki · Kawasaki, JP
• Ayako Ohno · Yokohama, JP
• Seiichi Hara · Kawasaki, JP
• Isao Abe · Kawasaki, JP

Key dates

• Filing date: Jun 20, 2012
• Grant date: Jan 29, 2013
• Expiry date: Jun 20, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P21/06
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A method of producing an α-L-aspartyl-L-phenylalanine-β-ester by forming the α-L-aspartyl-L-phenylalanine-β-ester from L-aspartic acid-α,β-diester and L-phenylalanine using an enzyme or enzyme-containing substance that has an ability to selectively link L-phenylalanine to an α-ester site of the L-aspartic acid-α,β-diester through a peptide bond.