Imaging methods and compositions comprising fluorescent dyes associated with viral components for nerve imaging
US8361775B2 · kind B2 · utility
45Cited by
1References
3Claims
0Family size
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Key dates
| Filing date | May 14, 2009 |
| Grant date | Jan 29, 2013 |
| Priority date | — |
| Expiry date | Sep 19, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K49/0097
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are compositions and methods for imaging nerve cells. The composition comprises a fluorescent dye; and a viral component selected from a neurotropic, replication-defective virus, a viral protein of a neurotropic virus, and a capsid of a neurotropic virus. Although the fluorescent dye in itself cannot penetrate nerve cells, the fluorescent dye is bound to the viral component to form a dye/viral component complex that is capable of penetrating nerve cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.