Patent · US Active

Hydroxy-bisphosphonic acid derivatives as vector targeting bone tissue

US8361993B2 · kind B2 · utility

1Cited by
2References
14Claims
0Family size

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Key dates

Filing dateJan 5, 2009
Grant dateJan 29, 2013
Priority date
Expiry dateSep 24, 2029

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07F9/5728
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to hydroxy-bisphosphonic acid derivatives corresponding to general formula (I): in which: -n and m denote, independently of one another, an integer ranging from 1 to 4, —X denotes an oxygen atom or an N—R3 group, —R1 and R3 denote, independently of one another, a linear or branched C1 to C6 alkyl group, and —R2 denotes a residue of a molecule of therapeutic or diagnostic interest, or pharmaceutically acceptable salts of said derivatives, and also the method for the preparation thereof and the therapeutic or diagnostic use thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.