Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis
US8362048B2 · kind B2 · utility
7Cited by
1References
24Claims
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Key dates
| Filing date | Nov 15, 2010 |
| Grant date | Jan 29, 2013 |
| Priority date | — |
| Expiry date | Nov 15, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds is provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.