Compounds and methods for treating protein folding disorders
US8362066B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Nov 19, 2007 |
| Grant date | Jan 29, 2013 |
| Priority date | — |
| Expiry date | Jan 22, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention is directed to compounds and methods for treating protein folder disorders. In certain embodiments the invention provides compounds and methods for treating neurodegenerative diseases such as Alzheimer's disease, tauopathy, cerebral amyloid angiopathy, Lewy body disease, dementia, Huntington's disease and prion-based spongiform encelopathy. The invention further provides compounds, methods and pharmaceutical compositions for inhibiting tau protein, Aβ protein or α-synuclein protein aggregation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.