3-aminoalkyl-1,3-dihydro-2H-indol-2-one derivatives, preparation thereof and therapeutic use thereof
US8362067B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Aug 18, 2010 |
| Grant date | Jan 29, 2013 |
| Priority date | — |
| Expiry date | Apr 21, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to novel 3-aminoalkyl-1,3-dihydro-2H-indol-2-one derivatives, to their preparation and to their therapeutic application.The compounds of the present invention correspond to the formula (I):in which the variables are as set forth in the specification.These compounds exhibit a strong affinity and a high selectivity for human arginine-vasopressin (AVP) V1a receptors and some compounds additionally exhibit a strong affinity for AVP V1b receptors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.