Patent · US Active

Method for selective localization of active agents at and in mitochondria and corresponding active agents

US8362243B2 · kind B2 · utility

0Cited by

1References

18Claims

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Assignee

Ugichem Gesellschaft fuer Organische Chemie mbH · AT

Inventors

Thomas Lindhorst · Munich, DE
Birgit Werner · Innsbruck, AT
Stefan Piper · Gã-Mamudo, GW

Key dates

Filing date	Oct 23, 2007
Grant date	Jan 29, 2013
Priority date	—
Expiry date	Oct 3, 2029

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02P20/55
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to novel methods for selective localization of active agents both at and in mitochondria within living cells, as well as corresponding active agents that penetrate through the cell membrane into the cells without further adjuvants and there can be localized both at and in mitochondria. These active agents are substituted with at least one monohydroxy mononitrophenyl rest or monohydroxy dinitrophenyl rest.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.