Patent · US Active

Method and system for microfluidic device and imaging thereof

US8367016B2 · kind B2 · utility

60Cited by
108References
23Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 27, 2012
Grant dateFeb 5, 2013
Priority date
Expiry dateJan 27, 2032

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/11
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A method for producing an image of an object within a chamber of a microfluidic device includes providing the microfluidic device having x, y, and z dimensions and a chamber depth center point located along the z dimension. The chamber depth center point is located a known z dimension distance from a fiducial marking embedded within the microfluidic device. The method also includes placing the microfluidic device within an imaging system that includes an optical device capable of detecting the fiducial marking. The optical device defines an optical path axially aligned with the z dimension and has a focal plane perpendicular to the optical path. When the focal plane is moved along the optical path, the fiducial marking is maximally detected when the focal plane is at the z depth in comparison to when the focal plane is not substantially in-plane with the z depth.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.