Antimicrobial material and method for making the same
US8367094B2 · kind B2 · utility
Inventor
Key dates
| Filing date | Feb 22, 2012 |
| Grant date | Feb 5, 2013 |
| Priority date | — |
| Expiry date | Feb 22, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2300/406
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides a modified catheter/indwelling device biomaterial that provides both immediate, and long-term microbiocidal effects on otherwise antibiotic-resistant strains of microorganisms. The material, which exhibits good mechanical performance characteristics for medical devices, is composed of a hydrophobic polyurethane (PU), a hydrophilic polyethylene vinyl acetate (PEVA) as an option, a soluble silver salt and a sparsely-soluble silver salt. The hydrophobic polyurethane provides the good physical properties, the PEVA the hydrophilicity necessary to allow some water ingress into the catheter, the soluble silver salt for an immediate burst effect, and the sparsely-soluble silver salt for sustained-release over many months postimplantation. Alternatively, the sparsely soluble silver salt can be silver iodate and is combined with silver sulfadiazine. Chlorhexidine can also be included in the material.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.