Nanocomposite hyaluronic acid-clay based hydrogels

US8367117B2 · kind B2 · utility

Assignees

• The Research Foundation of the State University of New York · US
• Polytechnic Institute of New York University · US

Inventors

• Miriam Rafailovich · Plainview, US
• Divya Bhatnagar · Stony Brook, US
• Mary K. Cowman · Potsdam, US

Key dates

• Filing date: May 10, 2011
• Grant date: Feb 5, 2013
• Expiry date: May 30, 2031

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2400/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Hydrogels formed from hyaluronic acid, a nanoclay and gelatin-type A. The hyaluronic acid is preferably dissolved in a cell culture medium containing amino acids, salts, glucose, vitamins and an antibiotic to form a hyaluronic acid solution. The gelatin-type A has a weight/volume of from about 0.02% to 0.08%. The nanoclay is exfoliated in deionized water and preferably includes SiO2, MgO, Na2O and Li2O.