Patent · US Active

Cross-linked compositions

US8367388B2 · kind B2 · utility

13Cited by

113References

36Claims

0Family size

Assignee

LIFEBOND LTD · IL

Inventors

Orahn Preiss Bloom · Jerusalem, IL
Ishay Attar · Ofakim, IL
Natalie Iram · Jerusalem, IL
Chagai Komlos · Haifa, IL
Meir Haber · Or Akiva, IL

Key dates

Filing date	Jun 18, 2009
Grant date	Feb 5, 2013
Priority date	—
Expiry date	Aug 25, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC08L89/06
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Improved compositions comprising a cross-linkable protein or polypeptide, and a non-toxic material which induces cross-linking of the cross-linkable protein. The compositions are optionally and preferably prepared in a non-phosphate buffer solvent. Optionally and preferably, the cross-linkable protein includes gelatin and any gelatin variant or variant protein as described herein. Optionally and preferably, the non-toxic material comprises transglutaminase (TG), which may optionally comprise any type of calcium dependent or independent transglutaminase, which may for example optionally be a microbial transglutaminase (mTG).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.