Methods and compositions related to internalizing RGD peptides
US8367621B2 · kind B2 · utility
9Cited by
1References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 16, 2009 |
| Grant date | Feb 5, 2013 |
| Priority date | — |
| Expiry date | Nov 21, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K7/64
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are compositions and methods useful for targeting tissue undergoing angiogenesis or to cells or tissue expressing αv integrins. The compositions and methods are based on peptide sequences that selectively bind to and home to tissue undergoing angiogenesis or to cells or tissue expressing αv integrins in animals. The disclosed targeting is useful for delivering therapeutic and detectable agents to tissue experiencing angiogenesis or to cells or tissue expressing αv integrins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.