Substituted 4-(1.2,3,4-tetrahydroisoquinolin-2-yl)-4-oxobutyric acid amide as KCNQ2/3 modulators

US8367700B2 · kind B2 · utility

Assignee

• Gruenenthal GmbH · DE

Inventors

• Sven Kühnert · St. Blasien, DE
• Gregor Bahrenberg · Monschau, DE
• Beatrix Merla · Aachen, DE
• Klaus Schiene · Goldkronach, DE
• Wolfgang Schröder · Aachen, DE

Key dates

• Filing date: Dec 11, 2009
• Grant date: Feb 5, 2013
• Expiry date: Feb 13, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to substituted tetrahydroisoquinolinyl-4-oxobutyric acid amides, methods for the preparation thereof, medicinal products containing these compounds and the use of these compounds for the preparation of medicinal products.