Protein disulfide isomerase assay method for the in vitro diagnosis of colorectal cancer
US8367806B2 · kind B2 · utility
0Cited by
5References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 9, 2009 |
| Grant date | Feb 5, 2013 |
| Priority date | — |
| Expiry date | Oct 30, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/99
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for the in vitro diagnosis of colorectal cancer by determining the presence of the protein disulfide isomerase tumor marker in a biological sample taken from a patient suspected of having colorectal cancer using at least one anti-PDI monoclonal antibody directed against a PDI epitope chosen from the epitopes of sequence SEQ ID NO: 1, SEQ ID NO: 2 with an aromatic amino acid having a three-dimensional structure similar to that of PDI, and SEQ ID NO: 3.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.