Methods for the treatment of radiation or chemotherapy-induced tissue damage
US8372389B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Nov 27, 2008 |
| Grant date | Feb 12, 2013 |
| Priority date | — |
| Expiry date | Nov 27, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/32
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to methods for preventing or treating toxicities associated with exposure to ionizing radiation or to chemotherapy. Particularly, the present invention relates to methods for preventing or treating toxicities associated with radiation or chemotherapy comprising administering to a subject in need of such treatment polypeptide complexes comprising an IL-6 linked to a soluble IL-6 receptor, the polypeptide complexes capable of preventing or treating toxicities, particularly xerostomia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.