Isolation and enumeration of cells from a complex sample matrix
US8372590B2 · kind B2 · utility
6Cited by
12References
36Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 7, 2009 |
| Grant date | Feb 12, 2013 |
| Priority date | — |
| Expiry date | Mar 28, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/54326
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to methods and systems for labeling, isolating, detecting and enumerating biological cells, or other biological analytes of interest present in a sample, where the capturing complex may also serve as a labeling agent. In one embodiment, the capture complex is an encoded magnetic bead coupled to antibodies having a specific affinity for a cell surface protein on a cell of interest. The methods and systems of the present invention can be used for quantitative or qualitative detection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.