GABA-steroid antagonists and their use for the treatment of CNS disorders
US8372824B2 · kind B2 · utility
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2References
6Claims
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Key dates
| Filing date | Feb 13, 2012 |
| Grant date | Feb 12, 2013 |
| Priority date | — |
| Expiry date | Feb 13, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/28
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds exhibiting 3alpha-hydroxy-5alpha/beta-steroid blocking action with no or only low antagonism against the gamma-aminobutyric acid (A) receptor (GABA-A), and compounds exhibiting partial antagonism against said receptor are presented. Methods for the prevention, treatment and/or alleviation of various CNS-disorders are suggested, as well as pharmaceutical compositions for such use.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.