Compounds as bradykinin B1 antagonists

US8372838B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Norbert Hauel · Schemmerhofen, DE
• Angelo Ceci · Mittelbiberach, DE
• Henri Doods · Warthausen, DE
• Ingo Konetzki · Warthausen, DE
• Juergen Mack · Biberach an der Riß, DE
• Henning Priepke · Warthausen, DE
• Annette Schuler-Metz · Ulm, DE
• Rainer Walter · Biberach, DE
• Dieter Wiedenmayer · Biberach an der Riß, DE

Key dates

• Filing date: Feb 22, 2011
• Grant date: Feb 12, 2013
• Expiry date: Apr 2, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formula Iwherein n, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and X are defined as described in the specification, which are bradykinin B1 antagonists, and their use as medicaments.