Inhibitors of the 11-beta-hydroxysteroid dehydrogenase type 1 enzyme
US8372841B2 · kind B2 · utility
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18References
13Claims
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Assignee
Inventors
Key dates
| Filing date | Aug 25, 2011 |
| Grant date | Feb 12, 2013 |
| Priority date | — |
| Expiry date | Aug 25, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/056
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to compounds which are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, and other diseases and conditions that are mediated by excessive glucocorticoid action.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.