Melanin-concentrating hormone receptor antagonists and methods of use

US8372848B2 · kind B2 · utility

Assignees

• Mixture Sciences, Inc. · US
• The Regents of the University of California · US

Inventors

• Richard A. Houghten · Del Mar, US
• Colette T. Dooley · San Diego, US
• Adel Nefzi · San Diego, US
• Zhiwei Wang · Beijing, CN
• Oliver Civelli · Portland, US
• Hiroshi Nagasaki · Nagoya, JP

Key dates

• Filing date: Mar 23, 2005
• Grant date: Feb 12, 2013
• Expiry date: Jun 15, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D233/42
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates generally to N-benzylamino cyclic thioureas, pharmaceutical compositions containing them, and their use as antagonists of melanin-concentrating hormone receptor (MCH receptor).