Purines as reverse transcriptase inhibitors
US8372852B2 · kind B2 · utility
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2References
20Claims
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Assignee
Inventors
Key dates
| Filing date | May 11, 2012 |
| Grant date | Feb 12, 2013 |
| Priority date | — |
| Expiry date | May 11, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D473/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Described herein are novel enzyme inhibitors. In some embodiments, the enzyme inhibitors are reverse transcriptase inhibitors, particularly HIV reverse transcriptase inhibitors. Also described herein are compositions containing them and methods of using them. Thus, the compounds and compositions described herein are useful for the in vitro and in vivo inhibition of HIV reverse transcriptase as a method of treating or preventing HIV, AIDS or related disorders. In some embodiments, the enzyme inhibitors are compounds of formula (I) or a pharmaceutically acceptable salt or tautomer thereof:
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.