Compounds which selectively modulate the CB2 receptor

US8372874B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Alessandra Bartolozzi · Norwalk, US
• Eugene Richard Hickey · Danbury, US
• Doris Riether · Biberach an der Riß, DE
• Lifen Wu · New Milford, US
• Renee M. Zindell · New Milford, US
• Monika Ermann · Wantage, GB

Key dates

• Filing date: Sep 22, 2009
• Grant date: Feb 12, 2013
• Expiry date: Apr 7, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of formula (I)are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.