Patent · US Active

Process for the preparation of dihydroquinazolines

US8372972B2 · kind B2 · utility

4Cited by

3References

2Claims

0Family size

Assignee

AiCuris GmbH & Co. KG · DE

Inventors

Käthe Gooβen · Kaiserslautern, DE
Oliver Kuhn · Konz, DE
Mathias Berwe · Sprockhövel, DE
Joachim Krüger · Mülheim an der Ruhr, DE
Hans-Christian Militzer · Odenthal, DE

Key dates

Filing date	Nov 30, 2011
Grant date	Feb 12, 2013
Priority date	—
Expiry date	Nov 30, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D239/80
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention relates to a process for the preparation of dihydroquinazolines, for example, methyl (S)-{8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoro -methyl)-phenyl]-3,4-dihydroquinazolin-4-yl}acetate (2S,3S)-2,3-bis[(4-methylbenzoyl) -oxy]succinic acid salt, which are used for the production of antiviral medicaments.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.