Salts of methyl 2-((R)-(3-chlorophenyl)((R)-1-((S)-2-(methylamino)-3-((R)-tetrahydro-2H-pyran-3-yl)propylcarbamoyl)piperidin-3-yl)methoxy)ethylcarbamate
US8372978B2 · kind B2 · utility
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15Claims
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Key dates
| Filing date | Aug 5, 2010 |
| Grant date | Feb 12, 2013 |
| Priority date | — |
| Expiry date | Feb 7, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Mucic acid salts of a compound represented by the following structural formula:are disclosed. In particular, single crystalline mucic acid salts of the compound represented by structural formula (I) are characterized by a variety of properties and physical measurements. Methods of producing the mucic acid salts, using the salts to antagonize one or more aspartic proteases, and methods of treating a number of aspartic protease mediated disorders using the salts are described herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.