Closed-loop micro-control system for predicting and preventing epileptic seizures
US8374696B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 13, 2006 |
| Grant date | Feb 12, 2013 |
| Priority date | — |
| Expiry date | Aug 3, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/0531
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The invention provides a micro-control neuroprosthetic device and methods for predicting and controlling epileptic neuronal activity. The device includes a detection system that detects and collects electrophysiological information comprising action potentials from single neurons and ensembles of neurons in a neural structure such as an epileptogenic region of the brain in a subject. An analysis system included in the neuroprosthetic device evaluates the electrophysiological information and performs a real-time extraction of neuron firing features from which the system determines when stimulus intervention is required. The neuroprosthetic device further comprises a stimulation intervention system that provides stimulus output signals having a desired stimulation frequency and stimulation intensity directly to the neural structure in which abnormal neuronal activity is detected. The analysis system further analyzes collected electrophysiological information during or following stimulus intervention to assess the effects of the stimulation intervention and to provide outputs to maintain or modify the stimulation intervention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.