Anti-P-selectin antibodies and methods of using the same to treat inflammatory diseases
US8377440B2 · kind B2 · utility
6Cited by
13References
7Claims
0Family size
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Key dates
| Filing date | Nov 30, 2007 |
| Grant date | Feb 19, 2013 |
| Priority date | — |
| Expiry date | Apr 28, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention features antibodies, e.g., chimeric and humanized antibodies, that recognize (i.e., bind) P-selectin. The P-selectin antibodies prevent P-selectin from binding to its cognate receptor. The P-selectin antibodies can be used to treat inflammatory and thrombotic conditions, e.g., sickle cell disease, pain crisis associated with sickle cell disease, deep vein thrombosis, asthma, rheumatoid arthritis, psoriasis, and ischemia reperfusion injury in a patient in need thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.