Patent · US Active

Substituted carbamoylmethylamino acetic acid derivatives as novel NEP inhibitors

US8377978B2 · kind B2 · utility

4Cited by
19References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 18, 2012
Grant dateFeb 19, 2013
Priority date
Expiry dateApr 18, 2032

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D261/14
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides a compound of formula I;or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R6, A1, A2, X1, s and m are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.