Crystalline pharmaceutical and methods of preparation and use thereof
US8378105B2 · kind B2 · utility
5Cited by
61References
14Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 21, 2010 |
| Grant date | Feb 19, 2013 |
| Priority date | — |
| Expiry date | Mar 9, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel crystalline polymorphic forms, Forms A, B, C, D, and E of a compound of Formula I, which has been found to be a potent inhibitor of LFA-1, are disclosed. Methods of preparation and uses thereof in the treatment of LFA-1 mediated diseases are also disclosed in this invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.