Combined automated parallel synthesis of polynucleotide variants
US8383346B2 · kind B2 · utility
116Cited by
18References
25Claims
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Key dates
| Filing date | Sep 18, 2009 |
| Grant date | Feb 26, 2013 |
| Priority date | — |
| Expiry date | Oct 30, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC40B50/06
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure relates to methods for efficient synthesis, cloning, transformation and screening of large diverse libraries of polynucleotide variants comprising well-defined nucleotide differences relative to a reference polynucleotide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.