Micro-bubble plate for patterning biological and non-biological materials
US8383378B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 9, 2006 |
| Grant date | Feb 26, 2013 |
| Priority date | — |
| Expiry date | Jul 8, 2028 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2300/0819
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Systems and methods are provided for patterning biological and non-biological material at specific sites on a plate, as well as growing three dimensional structures. Preferred embodiments comprise a plate with regions that will trap gas, usually in the form of bubbles, when the plate is submerged in liquid. Other embodiment of the present invention include a method for placing materials on the plate at pre-determined locations through the use of trapped gas to prevent materials from collecting at unwanted regions. The plate has great utility for plating cells and tissues at specific sites, such as on an array. The disclosed method can also be used to coat the surface of a plate with coatings at specific locations for patterned coating applications and to build up materials to produce three dimensional structures, including micro-mechanical structures—where the structures may be formed from living or non-living material, tissue or non-tissue, organic or inorganic, and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.