Method for producing hydroxylated adaivjantane using cytochrome P450
US8383381B2 · kind B2 · utility
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Key dates
| Filing date | Sep 25, 2008 |
| Grant date | Feb 26, 2013 |
| Priority date | — |
| Expiry date | Feb 11, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2603/74
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed is a method for producing a hydroxylated form of a compound having an adamantane skeleton, which is useful as an intermediate for functional resins and pharmaceutical products, with high yield and at low cost. Specifically, a hydroxylated form of a compound having an adamantane skeleton can be obtained by using cytochrome P450. More specifically, an N-(5-hydroxy-2-adamantyl)-benzamide derivative can be produced by hydroxylating an N-(2-adamantyl)-benzamide derivative.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.